Clinical Research: Fast Acting, Safe, & Natural Pain Relief Compared to Acetaminophen

When your patients are in pain, it’s understandable that they want relief, and they want it fast. Although a lot of attention has been paid to the safety risks and potential for addiction from prescription painkillers, there are deadly over-the-counter medicines (OTCs) hidden in plain sight, too. Acetaminophen is one of them.

Fortunately, clinical research shows that a combination of curcumin, boswellia, and black sesame oil is as fast and effective at fighting pain as this problematic drug, and all without causing risks to your patients’ health.

The Study Abstract:

Efficacy of high-dissolution turmeric-sesame formulation for pain relief in adult subjects with acute musculoskeletal pain compared to acetaminophen: A randomized controlled study.

Rudrappa GH, Chakravarthi PT, Benny IR. Medicine (Baltimore). 2020;99(28):e20373

Background: Acetaminophen (paracetamol) is one of the most commonly used over-the-counter drug for pain relief. Management of acute pain with plant-based nutrients has remained suboptimal due to an absence of data supporting acute relief of pain. In the present study, it was hypothesized that high-dissolution liquid treatment of black sesame extract oil, Curcuma longa and Boswellia serrata may provide pain relief in people with acute musculoskeletal pain as quickly as acetaminophen.

Method: In this randomized active controlled open label study, 88 healthy subjects with acute musculoskeletal pain were randomized to receive treatment capsule (Rhuleave-K; 1,000 mg/d) or 1,000 mg/d acetaminophen for 7 days. Change in pain intensity and pain relief at first 6 hours, 3 days, and 7 days were measured. The onset of analgesia was measured by perceptible pain relief and meaningful pain relief. Other measures were McGill Pain Questionnaire and Patient Global Impression Change.

Results: The treatment formulation resulted in average magnitude of pain relief comparable to the acetaminophen. Sixty-six percent of subjects in the treatment group reported positive response in pain relief (≥50% max TOTPAR; total pain relief) after 6 hours, compared to 73% of control. Seventy-three percent of subjects on treatment were considered positive responders, compared to 80% in the control group. The average time of onset of analgesia was 1 hour for the treatment group, versus 0.83 hour for control. At the end of day 3 and 7, there was significant improvement (P < .001 for day 3 and day 7) in the pain condition of the treatment group and was comparable to control (P = .436 for day 3 and P = .529 for day 7). The total McGill Pain score showed significant reduction in pain with the treatment irrespective of the pain intensity statistically equal (P = .468) to control. Both the groups were equal in providing sensory pain relief (P = .942), but the treatment was 8.57 times significantly better (P = .027) than acetaminophen in reducing the unpleasantness and emotional aspects (affective domain) involved with acute pain.

Conclusions: The results showed that the treatment used in the study may act as a natural, fast acting, and safe alternative for acute pain relief comparable to acetaminophen.

What This Means to Your Patients

72% Pain Reduction | Pain Reduction in Just One Hour

This groundbreaking clinical study on a unique combination of curcumin, boswellia, and black sesame oil proves that safe and effective relief without risks is possible and practical, providing a better course for patients who need to relieve acute (sudden onset) pain but are concerned about the side effects of over-the-counter drugs.

Time Tested Wisdom and Leading-Edge Science = Fast Pain Relief

The curcumin and boswellia combination in this study was specially emulsified in black sesame seed oil, which acts as a carrier, helping disperse these fat-soluble herbs into the intestines and bloodstream for optimal pain fighting ability. Additionally, black sesame seed oil also has a long history of use in Ayurvedic practice as an anti-inflammatory.

On the very first day of the study, the botanical combination virtually matched the perceived pain relief of acetaminophen, with noticeable relief in just one hour. By day seven of the study, the combination of curcumin, boswellia, and black sesame seed oil reduced pain by an average of 72 percent. Additionally, these botanicals were 8.5 times better than acetaminophen at reducing the emotional distress and unpleasantness associated with pain, something that the over-the-counter drug is notoriously unable to do.

There truly is a solution to pain that is safe and effective. This study shows that a combination of curcumin, boswellia, and black sesame seed oil delivers the same relief without the risks of acetaminophen, making it a smart choice for stopping acute pain.